hyaluronic acid
About hyaluronic acid
Hyaluronic acid injections use a substance naturally found in the body to improve facial hollows, restore volume, and refine contours.
Rather than simply filling wrinkles, this treatment enhances overall facial balance and dimension, creating a natural and more youthful appearance.
Effects of hyaluronic acid injections
Lifting effect
Plump up areas that have lost volume.
Shape nose, chin, tear troughs, lips, etc.
Skin elasticity
Recommended for
- To lift sagging skin
- To improve the wrinkles and sagging around the laugh lines, under the eyes, and around the mouth
- To plump up your face to eliminate the haggard looks (emaciation).
- I want to improve the flabbiness of my face line.
- I want to round out my forehead.
- I want to make my nose taller.
- I want to create eye bags.
- I want thick, plump lips.
- I want to reshape my chin.
- To eliminate the subtle unevenness of the contour line and to have firm skin
Characteristics of hyaluronic acid injections
POINT.01
What is the hyaluronic acid lift at the TOKICO Clinic?
TOKICO Clinic recommends hyaluronic acid lift using hyaluronic acid.
The hyaluronic acid lift is a balanced injection that adjusts the cause of sagging from the foundation.
Aging causes sagging due to skull reduction, fat and muscle loss, and loosening of the ligaments that support the subcutaneous tissue. Sagging causes collapse of the facial line, deepening of the laugh lines, and loosening of the mouth, resulting in deepening of the marionette lines.
In the past, hyaluronic acid injections were performed only for partial wrinkles and sagging, but by performing an anatomical 3D approach from the bone and fat layer, the root cause of aging, a balanced rejuvenation can be achieved from the foundation.
Popular areas of the face
Lifting power is enhanced by injecting hyaluronic acid layer by layer or in a plane shape, such as in deep fatty areas of the face.
By compensating for the loss of volume and creating a smooth rounded appearance, the shadow feeling is naturally softened and made more youthful.
We aim to lift up the skin by combining our original injection methods in such a way.
The clinic is also known for its design excellence.
POINT.02
Volume Improvement
The tissue around the cheeks, forehead, temples, and mouth atrophy and dimple, giving the appearance of a blowout.
The tissue around the cheeks, forehead, temples, and mouth atrophy and become hollow, giving the appearance of a blowout.
POINT.03
get treatments on parts of your face to obtain better facial balance
We also offer partial treatments such as chin augmentation, forehead rounding, nose enhancement, tear trough creation, lip plumping and corner of the mouth. We also advise our patients on the best design for their face during the consultation, and we treat them to shape the parts to their liking.
*The nose is injected only at the root of the nose. We do not inject hyaluronic acid into the nasal strips due to the risk of vascular embolization. （Nasal threads are safe and effective for raising and contouring the nasal bridge.)
Even if hyaluronic acid injections are simply called “hyaluronic acid injections,” a uniform treatment method will not produce the same results if the area to be injected or the condition of the face is different. In addition to the injection technique, we also understand the characteristics of each area and select the appropriate hyaluronic acid material for treatment.
We offer a wide variety of hyaluronic acid products and combine them according to the parts and conditions of the patient to achieve a natural-looking result that captures the individual characteristics of each patient.
The clinic is also known for its design excellence.
Types of hyaluronic acid fillers available at our clinic
Formulations designed with a focus on safety and natural integration
At our clinic, we primarily use high-purity formulations with minimal cross-linking agents and low levels of impurities.
- Designed to integrate naturally with the body
- Carefully selected to reduce the risk of inflammation and discomfort
- Aims to achieve a natural look and feel
We provide hyaluronic acid treatments with a strong emphasis on quality and safety.
High-purity, low-allergen formulations with a strong emphasis on safety
Neauvia Series / Maili Series
Hyaluronic acid is stabilized using a substance called a “cross-linking agent” to help it last longer.
While cross-linking agents are necessary, using them in excessive amounts may increase the likelihood of being recognized as a foreign substance by the body.
Hyaluronic acid with lower levels of cross-linking agents has the following characteristics:
- Integrates easily with the body
- Feels naturally soft to the touch
- Less likely to cause inflammation or discomfort
- Less likely to result in an unnatural appearance
In other words, it is hyaluronic acid that is not overly hardened for longevity—prioritizing natural results and safety.
Many allergic reactions are caused by cross-linking agents or impurities remaining from the manufacturing process.
Neauvia and Maili are characterized by low levels of cross-linking agents and extremely low impurities, making them less likely to be recognized as foreign substances by the body and therefore considered low-allergen.
Why effective results can still be achieved even with low levels of cross-linking agents
Hyaluronic acid needs to be stabilized with cross-linking agents to maintain its shape.
For this reason, some people may wonder:
“Does less cross-linking mean it will be absorbed quickly?”
“Will the results be less effective?”
However, with Neauvia and Maili, instead of relying on higher amounts of cross-linking agents, the quality and structure of the hyaluronic acid itself are optimized.
Reasons why effective results can still be achieved even with lower levels of cross-linking include:
- High purity of the hyaluronic acid
- A stable structure that helps maintain shape
- Designed to provide “support” rather than relying on excessive firmness
As a result, the product does not become unnecessarily hard, allowing for a natural, supportive lift from within—even to the touch—leading to a refined and high-quality finish.
NEAUVIA INTENSE RHEOLOGY
Blends smoothly into the skin, creating natural contour and volume in the cheeks and temples.
NEAUVIA INTENSE FLUX
Supports from within—helping improve sagging and achieve a natural lift.
MAILI Volume
Provides firm support—ideal for lifting the cheeks and defining the jawline.
MAILI Extreme
High shaping capacity—ideal for those who want to define the chin and create a sharper facial contour.
Basic type
Neuramis
In addition to the Neauvia and Maili series, our clinic also offers Neuramis, a hyaluronic acid filler with a long-standing track record of use.
It is suitable for a wide range of purposes, including wrinkle improvement and volume adjustment.
Thanks to its excellent integration and natural-looking results, it is often chosen by those new to hyaluronic acid treatments.
It is recommended for those who:
Want to make subtle adjustments
Prefer to treat only specific areas of concern
Provides hydration to the skin
Skin Enhancer
A new type of hyaluronic acid from the Neuramis series designed to enhance the skin’s moisture retention.
Unlike traditional fillers used for contouring, the Skin Enhancer is injected evenly into the superficial layer of the skin (dermis) to improve overall skin quality.
Hyaluronic acid has a strong ability to attract and retain moisture, helping to restore hydration, firmness, and smooth texture from within.
By replenishing hyaluronic acid that has decreased due to aging and dryness, it helps improve fine lines and dehydration, leading to a naturally plump, radiant complexion.
Neuramis Skin Enhancer is formulated for smooth integration into the skin, allowing it to distribute evenly within the superficial layers to improve overall moisture balance and skin texture.
Rather than dramatically altering facial structure, this treatment is ideal for those who:
Feel their skin has recently lost firmness or radiance
Are concerned about dryness or fine lines
Prefer subtle, natural-looking improvements
Various other items are available.
We understand the characteristics of hyaluronic acid formulations and select the appropriate formulation for the treatment area.
Particular about needles with consideration for downtime
The downtime of hyaluronic acid injections is internal bleeding. Because injections are performed, the risk of internal bleeding cannot be eliminated.
To avoid internal bleeding as much as possible, we are particular about the needles we use.
We use more than five different types of needles, ranging from hair-thin needles to cannulas with rounded tips that reduce the possibility of damaging blood vessels, depending on the material and the injection site.
Side Effects and Risks
Hyaluronic acid injections carry risks such as internal bleeding, erythema, and skin damage due to impaired blood flow.
Although internal bleeding cannot be completely avoided, we aim to avoid internal bleeding as much as possible through the selection of needles to be used and herbal medicines to prevent internal bleeding.
If internal bleeding occurs, rest assured that it will subside within one to two weeks.
The risk of vascular embolization from injections can be avoided through a thorough knowledge of anatomy and proficiency in technique, and we have hyaluronidase and prostaglandin on hand to prepare for any eventuality.
Case photograph
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Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
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Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
-
Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
-
Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
-
Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
-
Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
-
Pricing
Prices are shown as of the time of treatment.
Treatment Overview
Risks and Side Effects
Price
hyaluronic acid injection
Shinsaibashi / Umeda / Kyoto
| NEAUVIA / Maili | ~0.5ml | ¥55,000 |
| 0.6ml~ | ¥11,000/0.1ml | |
| Neuramis / Skin Enhancer | ~0.5ml | ¥44,000 |
| 0.6ml~ | ¥8,800 /0.1mlあたり | |
| eye bag HA 1 time | ¥55,000 |
All descriptions include tax
Questions
Can I take a bath or apply makeup after the treatment?
Makeup can be applied after the procedure. After the procedure, there is a possibility of internal bleeding due to increased blood flow. Therefore, we recommend showering only on the day of the procedure.
Can you give me anesthesia?
Yes, we use Anesthetic cream before the hyaluronic acid procedure. We use an anesthetic cream prior to the hyaluronic acid procedure. Anesthesia is included in the price of the hyaluronic acid procedure.
How long does the treatment take?
It depends on areas and the amount. If you have plans, please feel free to tell us.
When the effect wears off, will the wrinkles become deeper than before?
Injection of hyaluronic acid improves wrinkling and improves the skin’s ability to retain moisture, thereby reducing the appearance of wrinkles. Over time, hyaluronic acid is naturally absorbed and does not cause wrinkles to worsen.